Automated analysis of long-term grooming behavior in Drosophila using a k-nearest neighbors classifier
نویسندگان
چکیده
Despite being pervasive, the control of programmed grooming is poorly understood. We addressed this gap by developing a high-throughput platform that allows long-term detection of grooming in Drosophila melanogaster. In our method, a k-nearest neighbors algorithm automatically classifies fly behavior and finds grooming events with over 90% accuracy in diverse genotypes. Our data show that flies spend ~13% of their waking time grooming, driven largely by two major internal programs. One of these programs regulates the timing of grooming and involves the core circadian clock components cycle, clock, and period. The second program regulates the duration of grooming and, while dependent on cycle and clock, appears to be independent of period. This emerging dual control model in which one program controls timing and another controls duration, resembles the two-process regulatory model of sleep. Together, our quantitative approach presents the opportunity for further dissection of mechanisms controlling long-term grooming in Drosophila.
منابع مشابه
A comparative study of performance of K-nearest neighbors and support vector machines for classification of groundwater
The aim of this work is to examine the feasibilities of the support vector machines (SVMs) and K-nearest neighbor (K-NN) classifier methods for the classification of an aquifer in the Khuzestan Province, Iran. For this purpose, 17 groundwater quality variables including EC, TDS, turbidity, pH, total hardness, Ca, Mg, total alkalinity, sulfate, nitrate, nitrite, fluoride, phosphate, Fe, Mn, Cu, ...
متن کاملOptimized Seizure Detection Algorithm: A Fast Approach for Onset of Epileptic in EEG Signals Using GT Discriminant Analysis and K-NN Classifier
Background: Epilepsy is a severe disorder of the central nervous system that predisposes the person to recurrent seizures. Fifty million people worldwide suffer from epilepsy; after Alzheimer’s and stroke, it is the third widespread nervous disorder.Objective: In this paper, an algorithm to detect the onset of epileptic seizures based on the analysis of brain electrical signals (EEG) has b...
متن کاملA Novel Hybrid Approach for Email Spam Detection based on Scatter Search Algorithm and K-Nearest Neighbors
Because cyberspace and Internet predominate in the life of users, in addition to business opportunities and time reductions, threats like information theft, penetration into systems, etc. are included in the field of hardware and software. Security is the top priority to prevent a cyber-attack that users should initially be detecting the type of attacks because virtual environments are not moni...
متن کاملIdentification of selected monogeneans using image processing, artificial neural network and K-nearest neighbor
Abstract Over the last two decades, improvements in developing computational tools made significant contributions to the classification of biological specimens` images to their correspondence species. These days, identification of biological species is much easier for taxonomist and even non-taxonomists due to the development of automated computer techniques and systems. In this study, we d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 7 شماره
صفحات -
تاریخ انتشار 2018